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10. Mechanism of Action

 

    Morbid tissues are generally characterized by oxygen deficiency.  Accumulation of  H-radicals [free radicals -- Dr. Asai was FAR ahead of his time!] tends to destroy cells and tissues which gradually accumulate to cause disorders which in turn deteriorate in a morbid condition generated for various reasons. If oxygen could be selectively and  locally, fed to this lesion, oxygen would combine with  the accumulated H+ radicals to restore the deteriorated tissues, thereby cutting the vicious circle of accumulation of deteriorated tissues and disorders, restoring the normal functions of the tissues.
There is more on this page, right below, but this subject is so critically important that I urge you to click on the "Free Radical Next" link above, and start a series of pages that should explain this very vital data to you.  I have written and talked about "free radicals" for more than 20 years, including to many doctors and others who use the term as if they know it.  Yet, I find that a great many people have no idea of what that means, and even those who claim to be knowledgably can hardy ever explain it in terms that the average person can understand.  This special series, on free radicals, allows you to return to the home page for Dr. Asai's Book from any page of the series.  I URGE YOU TO STUDY THIS SERIES!
I'm not kidding.  This is the core of atomic physics as applied to health.  I've also created an electronic Study Aide, free, you can click on the image and take that electronic course.  It explains, with dozens of interactive questions and answers, exactly what is a free radical.

Here is an explanation of how the term "free radical" was arrived at:

Most organic molecules—those found in living things or their products—are fairly large. All of them are based on carbon and many consists of only carbon and hydrogen, or carbon, hydrogen and oxygen, linked up in chains or rings. Most organic molecules consist of a kind of basic structure of carbon atoms to which small clusters of other atoms are attached. These clusters, or chemical groups, are very important in chemistry, especially in biochemistry—the chemistry of living things—as different groups are responsible for most of the different chemical properties of the molecules.

In 1832 the German chemists Baron Von Liebig and Friedrich Wohler discovered that, when chemical reactions occurred, these little clusters, instead of breaking up to release the individual atoms of which they are made, tended to act almost like molecules in their own right, retaining their group identity and linking on, in their entirety, to other molecules. They did not, however, persist for any length of time on their own but always tried to tie themselves on to a molecule. It was decided to call these groups radicals. This word has no deep hidden meaning.

It simply comes from the Latin word radix, meaning 'a root', and was selected because the atom cluster hangs from the molecule like a root and can 'root' itself in other molecules.

As you may have guessed, free radicals are radicals that are temporarily unattached to a molecule. Unattached radicals are not happy just to sit around like the more stable molecules of compounds; rather they are constantly looking for something to latch on to. Many of them are quite small, consisting of only two or three atoms; some are larger. The one thing they all have in common is that they are remarkably active—and some of them are highly dangerous to our bodies.


    The basis of the theory of the mechanism of the compound is that germanium takes the form of a sesquioxide.

sesqui-

- \Ses`qui-\ [L., one half more, one and a half.] (Chem.) A combining form (also used adjectively) denoting that three atoms or equivalents of the substance to the name of which it is prefixed are combined with two of some other element or radical; as, sesquibromide, sesquicarbonate, sesquichloride, sesquioxide.

sesquioxide

\Ses`qui*ox"ide\, n. [Sesqui- + oxide.] (Chem.) An oxide containing three atoms of oxygen with two atoms (or radicals) of some other substance; thus, alumina, Al2O3 is a sesquioxide.

Oxygen readily combines with hydrogen, so it becomes apparent that hydrogen will strongly bind with the oxygen atoms of the compound, consequently bringing about a dehydrogenating reaction which is the mechanism by which germanium eliminates harmful substances causing disease in the body.

    Consider for a moment the basic fact of the life process whereby food is burned by the body to give energy, while carbon dioxide (C02) and hydrogen (H2) are created. CO2 is discharged from the lungs when we exhale, and H2 combines with oxygen to form water which is discharged in the urine and sweat. As mentioned previously, hydrogen may be referred to as a positive ion, which is as useless to the body as dust clogging the workings of a machine.
    To insure that the body functions normally, hydrogen must be removed, but for complete removal a large quantity of oxygen is needed. The germanium compound with its strong dehydrogenating effect takes the place of oxygen in combining with hydrogen to eliminate the latter from the body. In fact, all traces of germanium are discharged from the body through the digestive tract within 20 to 30 hours.

    As part of another experiment, tests were conducted on the effect of the germanium compound on the respiratory tissues of a group of mice using the Warburg method. Results obtained showed a remarkable decrease of oxygen consumption in the diaphragm and liver clear indication that the compound acted as a substitute for oxygen in combining with hydrogen. By the dehydrogenating or oxidizing action of the compound, not only hydrogen ions are removed from the blood, but abnormal proteins and other foreign matter are also removed. The oxidizing effect of the compound thus serves to purify the blood.

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